Influence of age on response to new generation blood-thinning medicines

Not Applicable

Completed

• Conditions: Anticoagulation response; Circulatory System

• Registration Number: ISRCTN65439252
• Lead Sponsor: ewcastle upon Tyne Hospitals Foundation Trust

Brief Summary

2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34658009/ (added 22/08/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2016-05-20
• Study Completion: 2018-04-01
• Last Update Posted: 5 September 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

Current inclusion criteria as of 21/09/2020:
Older subjects:
1. >65 years old
2. Medically stable
3. Without liver dysfunction
4. Able to give informed consent

Younger subjects:
1. <65 years of age
2. Healthy

Previous inclusion criteria:
Older subjects:
1. >65 years old
2. Medically stable
3. Without liver dysfunction
4. Able to give informed consent
5. Suspected of vitamin K deficiency as evaluated by the use of dietary questionnaire

Younger subjects:
1. <65 years of age
2. Healthy
3. Having a normal healthy diet as evaluated by the dietary questionnaire

Exclusion Criteria

1. Less than 18 years of age
2. Liver dysfunction
3. Receiving anticoagulation therapy

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Clotting time

Secondary Outcome Measures

Name	Time	Method
o secondary outcome measures