Does transcutaneous electrical acupoint stimulation alleviate remifentanil-induced hyperalgesia in patients undergoing thyroidectomy: a randomized controlled trial
Not Applicable
Completed
- Conditions
- hyperalgesiaAnaesthesiology - AnaestheticsNeurological - Other neurological disorders
- Registration Number
- ACTRN12615000496516
- Lead Sponsor
- Yusheng Yao, Department of Anesthesiology,Fujian Provincial Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
We enrolled 60 ASA I-II consecutive female subjects, aged 18 to 60 years, who scheduled for elective thyroidectomy under general anesthesia.
Exclusion Criteria
Potentially difficult airway, a history of chronic pain, drug or alcohol abuse, intake of any analgesic drug within 48 h before surgery, mental disorder, bradycadia, diabetes, pregnancy, and previous experience with acupuncture treatment.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome was mechanical pain threshold.<br>Mechanical pain threshold on the nondominant forearm and peri-incisional areas using electronic Von Frey Anesthesiometer (IITC Inc., Life Science Instruments, Woodland Hills, CA, USA ).[Mechanical pain threshold was assessed before surgery and postoperatively 0.5, 1, 2, 4 and 24 h. ]
- Secondary Outcome Measures
Name Time Method Postoperative pain intensity was rated with Visual Analogue Scale (VAS) ranging from 0 to 10, where 0 means no pain and 10 is the worst pain imaginable.[Postoperative pain intensity was rated at postoperative hours 0.5, 1, 2, 4 and 24.];The incidence of postoperative nausea and vomiting (PONV)[A patient will be considered to suffer from PONV if nausea or vomiting is documented in 24 h after surgery.]; The incidence of dizziness[The incidence of dizziness was evaluated in 24 h postoperatively.]