Intensive Care Unit (ICU) Admission Decisions in the Elderly : the ICE-CUB Study

Completed

• Conditions: Patient Admission; Death; Activities of Daily Living
• Interventions: Other: Intensive Care Unit admission

• Registration Number: NCT00912600
• Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Brief Summary

Percentage of patients over 80 admitted in ICU varies greatly from one center to another. ICU admission criteria of older patients are scarcely described and benefit of ICU admission for those patients is uncertain. In this study, we prospectively studied old patients arriving to the emergency department of 15 French hospitals with conditions that potentially warrant ICU admission.The working hypothesis was that ICU admission was associated with a 20% decrease in six-month mortality.

Detailed Description

This was a prospective multicenter observational cohort study of elderly individuals presenting to one of 15 emergency departments and possibly qualifying for admission to an ICU. To be included, subjects had to be aged at least 80 years and be diagnosed by the ED physician with one of 74 conditions potentially warranting ICU admission.Outcome studied are ICU eligibility as assessed by emergency and ICU physicians, hospital and six-month death and changes in functional status in the six month following emergency department visit.

Study Timeline

• Study Start: 2004-11
• Primary Completion: 2006-01
• Study Completion: 2009-02
• Status Verified: 2009-05
• Study First Submitted: 2009-06-02
• Study First Submitted QC: 2009-06-02
• Study First Posted: 2009-06-03
• Last Update Submitted: 2012-07-25
• Last Update Posted: 2012-07-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2643

Inclusion Criteria

• Age over 80
• Be assigned by the emergency physician with one of 74 conditions potentially warranting ICU admission

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Exclusion Criteria

• Patient's refusal

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
1	Intensive Care Unit admission	Elderly individuals presenting to one of 15 emergency departments and possibly qualifying for admission to an ICU

Primary Outcome Measures

Name	Time	Method
ICU eligibility as assessed by emergency and ICU physicians	At the admission

Secondary Outcome Measures

Name	Time	Method
Change in functional status	During 6 months
Six-month death	During 6 months after the end of the hospitalisation
Hospital death	During the hospitalisation

Trial Locations

Locations (1)

Hôpital Saint-Antoine; 🇫🇷 Paris, France