Comparison of Vascular Risk in Patients Treated for Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS) With Continuous Positive Airway Pressure (CPAP) and Mandibular Advancement Orthosis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Obstructive Sleep Apnea/Hypopnea Syndrome
- Sponsor
- Centre Hospitalier de Valence
- Enrollment
- 172
- Locations
- 1
- Primary Endpoint
- morbimortality vascular criteria
- Status
- Completed
- Last Updated
- 7 months ago
Overview
Brief Summary
a monocentric,non interventional, prospective study to compare cardiovascular risk in patients with Obstructive Sleep Apnea/Hypopnea Syndrome treated with Continuous Positive Airway Pressure (CPAP) and Mandibular Advancement Orthosis.
Detailed Description
The first-line treatment of severe Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS) is nocturnal ventilation with Continuous Positive Airway Pressure (CPAP). and The second-line treatment is the mandibular advancement orthosis (MAO)\]. CPAP is the most effective treatment to reduce the apnea-hypopnea index (AHI). However, its tolerance is sometimes difficult, causing many discontinuations. The purpose of this review is to evaluate a vascular morbimortality criteria: * Cardiovascular: myocardial infarction, heart failure, rhythm disorder * Neurological: transient or non transient stroke * ophthalmologic: anterior ischemic optic neuropathy, occlusion of the central artery or central retinal vein occlusion
Investigators
Eligibility Criteria
Inclusion Criteria
- •Obstructive Sleep Apnea/Hypopnea Syndrome treated with With Continuous Positive Airway Pressure (CPAP) or Mandibular Advancement Orthosis
- •Age ≥ 18 years old
- •Read, write and understand the French language
Exclusion Criteria
- •Patient under guardianship, deprived of liberty, safeguard of justice
- •Refusal to participate in research
Outcomes
Primary Outcomes
morbimortality vascular criteria
Time Frame: up to 6 months
Presence or absence of ophthalmologic event