Comparison of Vascular Risk in Patients Treated for Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS) With Continuous Positive Airway Pressure (CPAP) and Mandibular Advancement Orthosis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 172
- 试验地点
- 1
- 主要终点
- morbimortality vascular criteria
研究概览
简要总结
a monocentric,non interventional, prospective study to compare cardiovascular risk in patients with Obstructive Sleep Apnea/Hypopnea Syndrome treated with Continuous Positive Airway Pressure (CPAP) and Mandibular Advancement Orthosis.
详细描述
The first-line treatment of severe Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS) is nocturnal ventilation with Continuous Positive Airway Pressure (CPAP). and The second-line treatment is the mandibular advancement orthosis (MAO)].
CPAP is the most effective treatment to reduce the apnea-hypopnea index (AHI). However, its tolerance is sometimes difficult, causing many discontinuations.
The purpose of this review is to evaluate a vascular morbimortality criteria:
- Cardiovascular: myocardial infarction, heart failure, rhythm disorder
- Neurological: transient or non transient stroke
- ophthalmologic: anterior ischemic optic neuropathy, occlusion of the central artery or central retinal vein occlusion
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Obstructive Sleep Apnea/Hypopnea Syndrome treated with With Continuous Positive Airway Pressure (CPAP) or Mandibular Advancement Orthosis
- •Age ≥ 18 years old
- •Read, write and understand the French language
排除标准
- •Patient under guardianship, deprived of liberty, safeguard of justice
- •Refusal to participate in research
结局指标
主要结局
morbimortality vascular criteria
时间窗: up to 6 months
Presence or absence of ophthalmologic event
次要结局
未报告次要终点