Physical Activity Level and Sleep Quality in Type 2 Diabetes

Not Applicable

Completed

• Conditions: Type 2 Diabetes Mellitus (T2DM); Exercise; Sleep; Biomarkers / Blood; Type 2 Diabetes Mellitus (T2DM); Sleep; Biomarkers / Blood; Physical Activity Level
• Interventions: Other: Biomarkers / blood; Other: Questionnaire

• Registration Number: NCT06602778
• Lead Sponsor: Selcuk University

Brief Summary

In this study, we investigated the effects of physical activity level and sleep quality level on total antioxidant level (TAS), total oxidant level (TOS), Malondialdehyde (MDA) and Superoxide Dismutase (SOD) which are markers of oxidative stress, irisin, fibronectin type III-protein 5 (FNDC5).

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-09
• Study First Submitted: 2024-09-17
• Study First Submitted QC: 2024-09-17
• Study First Posted: 2024-09-19
• Study Start: 2024-09-20
• Primary Completion: 2024-10-20
• Study Completion: 2025-02-25
• Last Update Submitted: 2025-03-15
• Last Update Posted: 2025-03-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Being between 30-65 years old
• Volunteering to participate in the study
• Being literate
• Being diagnosed with Type 2 Diabetes

Exclusion Criteria

• Having a physical or mental illness that prevents communication
• malignant disease,
• infectious disease,
• chronic obstructive pulmonary disease,
• liver disease,
• patients with kidney disease and joint or muscle disease will not be included

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
T2DM-BMI3	Biomarkers / blood	-
T2DM-BMI0	Biomarkers / blood	-
T2DM-BMI0	Questionnaire	-
T2DM-BMI1	Biomarkers / blood	-
T2DM-BMI1	Questionnaire	-
T2DM-BMI2	Biomarkers / blood	-
T2DM-BMI2	Questionnaire	-
T2DM-BMI3	Questionnaire	-

Primary Outcome Measures

Name	Time	Method
biomarkers derived from blood sera	10 Minutes	blood glucose, total cholesterol, triglycerides, LDL and HDL analyzes
ELISA method of oxidative stress markers	10 minutes	All reagents of the ELISA kits of the oxidative stress markers TAS, TOS, MDA and SOD will be brought to room temperature. Standards will be prepared according to the protocol and added to a 96-well plate with the samples. Buffer solution will be added to each well and incubated for 90 min at room temperature. After each step, necessary washes will be performed and finally chromogenic agents will be added and read spectrophotometrically. Although the timing and additions may vary according to the parameter, in general the procedure is as indicated. Each sample will be run 2 times for both TAS and TOS
Analysis of exercise-related markers by ELISA method	10 minutes
International Physical Activity Questionnaire	5 minutes
Pittsburgh Sleep Quality Index	5 minutes

Trial Locations

Locations (1)

Selcuk University; 🇹🇷 Konya, Selcuklu, Turkey