NCT01292590已完成不适用
Use of Closed Loop Control to Examine the Effect of Changes in Dietary Fat Intake on Insulin Requirements and Glucose Control
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Change in insulin requirements
研究概览
简要总结
The purpose of this study is to determine if dietary fat alters insulin requirements in type 1 diabetes.
详细描述
This cross-over prospective study will require a two day admission to the clinical research center. Subjects will undergo closed loop glucose control and will received a diet with controlled macronutrient content.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •type 1 diabetes using insulin pump and CGM
排除标准
- •renal or hepatic failure
- •cancer or lymphoma
- •malabsorption or malnourishment
- •hypercortisolism
- •alcoholism or drug abuse
- •anemia (hematocrit < 36 in females and <40 in males)
- •eating disorder
- •dietary restrictions
- •Acetaminophen allergy
- •Chronic acetaminophen use
- •Glucocorticoid therapy
研究组 & 干预措施
High fat meal
Experimental
干预措施: High fat meal (Other)
结局指标
主要结局
Change in insulin requirements
时间窗: postprandially until 8 hours
次要结局
未报告次要终点
研究者
研究点 (1)
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