Role of Cardiac AngioMR in Diagnosis of Cardiac and Vascular Anomalies in Adult Patients with Turner Syndrome

Recruiting

• Conditions: Anomaly Heart; Turner Syndrome

• Registration Number: NCT06178887
• Lead Sponsor: Azienda Ospedaliero-Universitaria di Modena

Brief Summary

Considering the high prevalence of cardiovascular disease in Turner syndrome patients, noninvasive cardiac imaging is crucial for diagnosis and follow-up. From the review of the literature, it was evident that the imaging techniques used involved the evaluation of only the thoracic findings, in particular the heart and the thoracic aorta, while no data are currently available on the distal abdominal aorta or iliac arteries, since ultrasound and MRI are interrupted at the diaphragmatic level.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-01-08
• Study First Submitted: 2023-11-27
• Study First Submitted QC: 2023-12-11
• Study First Posted: 2023-12-21
• Status Verified: 2025-03
• Last Update Submitted: 2025-03-12
• Last Update Posted: 2025-03-14
• Primary Completion: 2025-12-31
• Study Completion: 2025-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 33

Inclusion Criteria

• confirmed diagnosis of Turner Syndrome
• patients underwent angioMR 1.5 T
• age > 18 years

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Vascular and cardiac anomalies	5 years	description of the main cardiovascular anomalies found by MRI at the thoracic and abdominal level anomalies in terms of supernumeray arteries and/or veins and measurement of length and diameters of main vascular tracts (e.g. ascending, descending aorta, aortic arch, renal arteries...) or vascular congenital abnormalities

Trial Locations

Locations (1)

Unit of Endocrinology of Azienda Ospedaliera-Universitaria di Modena; 🇮🇹 Modena, Italy