Botulinum Toxin for the Treatment of Involuntary Movement Disorders

Recruiting

• Conditions: Movement Disorders

• Registration Number: NCT00001208
• Lead Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 1999-11-3
• Last Update Posted: 23 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 2000

Inclusion Criteria

INCLUSION CRITERIA:<br><br> 1. Patients 2 years and older, will be eligible for participation if they have a<br> disorder that, in the judgment of the treating physician, might be amenable to<br> treatment with BTX.<br><br> 2. Applicable disorders include but are not limited to dystonia, hemifacial spasm,<br> blepharospasm, tremor, spasmodic dysphonia, tics, vocal fold tremor, oral<br> lingual dyskinesia, tardive dyskinesia, spasticity, and spasmodic dysphonia.<br><br>EXCLUSION CRITERIA:<br><br> 1. Women who are planning on becoming pregnant, are pregnant or breastfeeding, for the<br> duration of the condition.<br><br> 2. Subjects who require treatment with an aminoglycoside antibiotic, until treatment is<br> complete.<br><br> 3. For laryngeal injections, subjects must have a paradoxical vocal fold movement with<br> intermittent stridor due to either gastroesophageal reflux or emotional disorders.

Exclusion Criteria

Not provided

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Study Natural History- data analysis;Maintain cohort of subjects