ISRCTN77607163CompletedNot Applicable
A comparison of pre-medication with oral paracetamol versus intravenous paracetamol given at time of induction for post-operative analgesia following wisdom tooth extraction
Queen Victoria Hospital NHS Foundation Trust (UK)0 sites116 target enrollmentStarted: May 9, 2008Last updated:
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 116
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •Patients over 18 years (either sex) having a general anaesthetic for extraction of wisdom teeth of which at least one must be a lower molar tooth.
Exclusion Criteria
- •1. Patients who are unable to give full consent, or who do not wish to take part in the trial
- •2. Patients who have a baseline Visual Analogue Scale (VAS) score of more than zero
- •3. Patients unable to swallow tablets
- •4. Patients who have taken simple analgesics that day, prior to surgery
- •5. Hypersensitivity or history of serious adverse reactions to paracetamol or non-steroidal anti-inflammatory drugs
- •6. Active liver disease
- •7. Renal dysfunction
- •8. Pregnant or breast feeding women
- •9. Alcohol or drug abuse
- •10. History of unresponsiveness to paracetamol
- •11. Gastric or peptic ulcer disease
- •12. Inflammatory bowel disease
- •13. Blood coagulation abnormalities
Investigators
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