Postoperative Pain in Neonates After Abdominal Surgery Using Quadratus Lumborum Block

• Conditions: Postoperative Pain
• Interventions: Procedure: General anesthesia; Procedure: Quadratus lumborum block

• Registration Number: NCT03203031
• Lead Sponsor: Hôpital Armand Trousseau

Brief Summary

Postoperative pain scores and analgesic requirements will be evaluated in neonates after abdominal surgery, with regional quadratus lumborum block performed at the beginning of the procedure.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-06-19
• Study First Submitted QC: 2017-06-28
• Study First Posted: 2017-06-29
• Study Start: 2017-06-30
• Status Verified: 2020-07
• Last Update Submitted: 2020-07-07
• Last Update Posted: 2020-07-08
• Primary Completion: 2021-07-01
• Study Completion: 2021-10-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• abdominal surgery under general anesthesia
• spontaneously breathing before the procedure

Exclusion Criteria

• multiple organ failure
• mechanical ventilation before the procedure

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Neonates with abdominal surgery and quadratus lumborum block	General anesthesia	0-6 months children with abdominal surgery. After standard induction of general anesthesia, patients will receive 0.5 ml/kg of ropivacaine (2 mg/ml) in a quadratus lumborum block. Ultrasonography will be used to guide the injection. In the postoperative period, pain scores and analgesics consumption will be recorded until the 48th hour post surgery.
Neonates with abdominal surgery and quadratus lumborum block	Quadratus lumborum block	0-6 months children with abdominal surgery. After standard induction of general anesthesia, patients will receive 0.5 ml/kg of ropivacaine (2 mg/ml) in a quadratus lumborum block. Ultrasonography will be used to guide the injection. In the postoperative period, pain scores and analgesics consumption will be recorded until the 48th hour post surgery.

Primary Outcome Measures

Name	Time	Method
morphine consumption	At the 24th hour after surgery	cumulative morphine dose administered to the patient
nalbuphine consumption	At the 24th hour after surgery	cumulative nalbuphine dose administered to the patient
postoperative pain score	At the 24th hour after surgery	standard pain scale used in neonatology in our institution: EVENDOL (EValuation ENfant Douleur)

Secondary Outcome Measures

Name	Time	Method
morphine consumption	At the 48th hour after surgery	cumulative morphine dose administered to the patient
nalbuphine consumption	At the 48th hour after surgery	cumulative nalbuphine dose administered to the patient

Trial Locations

Locations (1)

Hopital Armand Trousseau; 🇫🇷 Paris, France