Comparison of Three Scoring Systems for Prediction of Mortality in Patients Admitted to the Intensive Care Unit With Manifest Tetanus
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 115
- 试验地点
- 1
- 主要终点
- Death from any cause.
研究概览
简要总结
Three scoring systems will be applied to patients suffering from manifest tetanus and will be related to mortality.
详细描述
On admission to the intensive care unit, three scoring systems for tetanus severity will be applied to all patients: the Tetanus Severity Score (TSS), Dakar Score, and Philips Score, and will then be related to the occurrence of in-hospital mortality or survival to hospital discharge.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults (age 18 years old or more).
- •Any sex (male or female), regardless of gender identity.
- •Diagnosis of manifest tetanus according to the WHO criteria (https://www.who.int/news-room/fact-sheets/detail/tetanus), that is the presence of one or both of the following criteria with or without the history of specific wound or injury:
- •Sustained spasm of the facial muscles in which person appears grinning.
- •Painful muscular contractions
排除标准
- •Age < 18 years.
- •Absent criteria of manifest tetanus, as per the WHO criteria (https://www.who.int/news-room/fact-sheets/detail/tetanus).
- •Incomplete medical record with missing data required to calculate the Tetanus Severity Score, Philips Score, or Dakar score.
- •Incomplete medical record with missing data regarding the primary outcome measure (survival to hospital discharge or in-hospital mortality).
研究组 & 干预措施
Non-survivors
Patients who die in hospital
干预措施: Tetanus Severity Score (TSS) (Diagnostic Test)
Non-survivors
Patients who die in hospital
干预措施: Philips Score (Diagnostic Test)
Non-survivors
Patients who die in hospital
干预措施: Dakar Score (Diagnostic Test)
Survivors
Patients who survive to hospital discharge
干预措施: Tetanus Severity Score (TSS) (Diagnostic Test)
Survivors
Patients who survive to hospital discharge
干预措施: Philips Score (Diagnostic Test)
Survivors
Patients who survive to hospital discharge
干预措施: Dakar Score (Diagnostic Test)
结局指标
主要结局
Death from any cause.
时间窗: From the date of onset of symptoms until the date of death or date of discharge from the hospital, whichever comes first, assessed up to 90 days.
Occurrence of death from any cause, assessed from the date of onset of symptoms up to 90 days.
次要结局
未报告次要终点
研究者
Sameh M. Hakim
Professor of Anesthesiology, Intensive Care and Pain Management
Ain Shams University