Prevalence of Covid-19 in Children Admitted to Paediatric Emergency Departments During the Pandemic Period in France

Completed

• Conditions: COVID; Infection Viral; Coronavirus
• Interventions: Diagnostic Test: nasopharyngeal swab

• Registration Number: NCT04336761
• Lead Sponsor: University Hospital, Lille

Brief Summary

Arriving in December 2019, Coronavirus COVID-19 infection is causing a global pandemic with high morbidity and mortality among adults and especially seniors. The child appears little or no affected by this infection. It is estimated that the child could be asymptomatic or pauci-symptomatic carrier and thus be vector of the disease. For this reason, measures have been taken to close schools and contain populations in a large number of countries, including France. However, there are no data on the prevalence of COVID-19 in children.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-04-03
• Study First Submitted QC: 2020-04-03
• Study First Posted: 2020-04-07
• Study Start: 2020-04-15
• Primary Completion: 2021-01-01
• Study Completion: 2021-01-01
• Status Verified: 2021-03
• Last Update Submitted: 2021-03-10
• Last Update Posted: 2021-03-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 901

Inclusion Criteria

• 1st Line Consultation in Pediatric Emergencies
• All reasons for consultation during working hours
• Informed and written consent of a parent holder (only 1 authorized companion) and a child of understanding age

Exclusion Criteria

• Refusal of participation by parents/child of decision age
• No membership of a social security scheme (beneficiary or entitled)
• No understanding of French

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Child suspected of infection with COVID-19.	nasopharyngeal swab	Child included with positive included

Primary Outcome Measures

Name	Time	Method
Prevalence of positivity of COVID-19 virus measured by rt-PCR	At 28 days

Secondary Outcome Measures

Name	Time	Method
Percentage of children hospitalized tested within 28 day	through study completion, an average 28 days
Respiratory signs of children tested within 28 day	through study completion, an average 28 days
Contact frequency	At inclusion	the degree of relationship with these contacts and the time spent in contact with them within 24 hours before emergency
Prevalence of positivity of other respiratory viruses measured by rt-PCR	at 28 days
Prevalence of positivity of COVID-19 virus measured by rt-PCR in the following subpopulations of emergency patients	at the end an average 28 days	children admitted to pediatric emergencies for respiratory signs; * Children hospitalized as a result of travelling to pediatric emergency departments for respiratory signs; * Respiratory asymptomatic children admitted to pediatric emergencies

Trial Locations

Locations (6)

Hôpital Mère Enfant CHU; 🇫🇷 Nantes, France

CH Louis MOURIER; 🇫🇷 Colombes, France

Hôpital Jeanne de Flandres, CHU; 🇫🇷 Lille, France

Hôpitaux Pédiatriques de Nice CHU-Lenval; 🇫🇷 Nice, France

CHU de Tours; 🇫🇷 Tours, France

Hôpital des enfants - CHU; 🇫🇷 Toulouse, France