The effect of oral melatonin before percutaneous nephrolithotomy surgery
Phase 3
- Conditions
- Kidney stones.Calculus of lower urinary tract
- Registration Number
- IRCT20190624043991N26
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 104
Inclusion Criteria
Patients in the age range of 20 to 55 years
Candidate for PCNL surgery under general anesthesia
Written and informed consent from patients
Exclusion Criteria
Neuro-psychiatric diseases such as depression and schizophrenia
Heart diseases and brain treatment
The use of sedatives and beta blockers and sleeping pills or pain relievers
Existence of drug sensitivity
Estimated duration of anesthesia>4 hours
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in the incidence of SIRS caused by percutaneous nephrolithotomy (PCNL) due to the use and non-use of melatonin. Timepoint: 24 to 48 hours after the operation. Method of measurement: Medical laboratory.;Changes in the incidence of sepsis caused by percutaneous nephrolithotomy (PCNL) due to the use and non-use of melatonin. Timepoint: 24 to 48 hours after the operation. Method of measurement: Medical laboratory.
- Secondary Outcome Measures
Name Time Method