跳至主要内容
临床试验/NCT06107257
NCT06107257招募中不适用

Cardiogenic Acute Pulmonary Edema in Subjects Over 75 Years Old: Impact of Non-invasive Ventilation on Mortality

University Hospital, Strasbourg, France1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2023年2月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
200
试验地点
1
主要终点
Survival Analysis

研究概览

简要总结

People aged over 75 represent almost 10% of the general population, and 12 to 14% of patients consulting emergency departments. Cardiogenic acute pulmonary edema (APO) is a very common reason for admission to the emergency room. The effectiveness of non-invasive ventilation (NIV) has been demonstrated during the management of PAO and would allow, compared to medical treatment alone, a more rapid improvement in clinical and gasometric parameters as well as a reduction in the need for ventilation. orotracheal intubation. On the other hand, the impact of NIV on mortality in cardiogenic PAO seems poorly defined, with lower levels of scientific evidence regarding a possible benefit in terms of survival, particularly in the elderly population.

The objective of this study is to determine whether the use of NIV in cardiogenic PAO in elderly subjects admitted to the emergency room of Strasbourg University Hospital would have an impact in terms of mortality up to 6 months compared to medical treatment alone.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Retrospective

入排标准

年龄范围
76 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adult subject (> 75 years old)
  • Admission to the NHC emergency room between January 1, 2021 and October 31, 2021
  • Diagnosis of cardiogenic PAO
  • Indication of NIV according to current recommendations
  • Subject not opposing the reuse of their data for scientific research purposes.

排除标准

  • Subject having expressed his opposition to the reuse of his data for scientific research purposes.
  • Presence of an absolute contraindication to NIV
  • Respiratory distress due to pneumonia or other diagnosis
  • RT-PCR Sars Cov 2 positive in emergency

结局指标

主要结局

Survival Analysis

时间窗: 6 months after cardiogenic acute pulmonary edema

次要结局

未报告次要终点

研究者

发起方
University Hospital, Strasbourg, France
申办方类型
Other
责任方
Sponsor

研究点 (1)

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