NL-OMON38625
Completed
Not Applicable
Assessment of pharmacokinetics and pharmacokinetic drug-drug interaction with ketoconazole of the metabolite S 41015 after single oral unlabelled microdoses of S 41015 and i.v. radiolabelled microdoses of [14C]-S 41015, and pharmacokinetics of S 38844 after single oral unlabelled microdose of S 38844 and i.v. radiolabelled microdose of [14C]-S 38844 in healthy male participants - S 41015 and S 38844 microdosing study
Institut de Recherches Internationales Servier I.R.I.S0 sites6 target enrollmentTBD
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- hart- en vaatziekten
- Sponsor
- Institut de Recherches Internationales Servier I.R.I.S
- Enrollment
- 6
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •healthy male Caucasian subjects,
- •non\-smoking or smoking less then 5 cigarettes per day,
- •EM for CYP2C9,
- •18 \- 45 yrs, inclusive,
- •18\.5 \- 30\.0 kg/m2, inclusive
Exclusion Criteria
- •Suffering from hepatitis B, hepatitis C, cancer or HIV/AIDS. In case of participation in another drug study within 90 days before the start of this study or being a blood donor within 3 months from the start of the study.
Outcomes
Primary Outcomes
Not specified
Similar Trials
Not yet recruiting
Not Applicable
A study on the pharmacokinetics and pharmacodynamics of remimazolam during total intravenous anesthesia with remifentanilNot ApplicableKCT0007066Inje University Busan Paik Hospital15
Completed
Not Applicable
The evaluation of pharmacokinetic and pharmacodynamic properties of Propiverine Hydrochloride transdermal formulatiooveractive bladderJPRN-UMIN000011937Dept of Clinical Pharmacology and Therapeutics, Oita University Faculty of Medicine10
Active, not recruiting
Not Applicable
Evaluation of blood drug level profile, effect and safety after repeated administration of a slow release formulation of S-38844 in healthy male volunteersEUCTR2010-020197-42-DEInstitut de Recherches Internationales Servier27
Completed
Not Applicable
Analysis of pharmacokinetics and pharmacodynamics for capecitabine during new chemotherapy regimen by bevacizumab (Bev) in combination with XELOX in unresectable colorectal cancerunresectable colorectal cancerJPRN-UMIN000013038Tsukasa Hotta10
Active, not recruiting
Not Applicable
Evaluation of pharmacokinetic and pharmacodynamic interactions between escitalopram and drugs used for the treatment of bipolar disorders. - NDbipolar disordersMedDRA version: 9.1Level: LLTClassification code 10057667Term: Bipolar disorderEUCTR2008-000370-20-ITAZIENDA OSPEDALIERA PISANA