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Clinical Trials/NCT01071629
NCT01071629
Unknown
Not Applicable

Aerobic Interval Training Versus Combined Aerobic Interval Training and Strength Training Effects in Patients With Heart Failure

University of Athens1 site in 1 country40 target enrollmentNovember 2004

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Chronic Heart Failure
Sponsor
University of Athens
Enrollment
40
Locations
1
Primary Endpoint
Aerobic exercise capacity
Last Updated
11 years ago

Overview

Brief Summary

Chronic heart failure (CHF) is a common syndrome characterized by several central hemodynamic and peripheral vascular and muscle abnormalities including autonomic imbalance, neuro-hormonal over-activation and decreased oxidative status.

In patients suffering from CHF, exercise confers several beneficial effects on the cardiovascular and peripheral systems, mainly by continuous aerobic training. However, interval aerobic training has also been validated as an alternate form of training that increases the exercise capacity of patients who are in CHF.

Recent studies have suggested that resistance training alone or as a complementary program besides the traditionally aerobic continuous training might exert favorable effects. However, little it is known about the combined effects of interval and strength training in CHF patients.

Aim of this prospective randomized controlled study was to investigate the effects of combined interval and strength training comparing to interval training alone in CHF patients.

Registry
clinicaltrials.gov
Start Date
November 2004
End Date
September 2015
Last Updated
11 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
University of Athens
Responsible Party
Principal Investigator
Principal Investigator

Serafim Nanas

MD

University of Athens

Eligibility Criteria

Inclusion Criteria

  • Stable systolic heart failure
  • NYHA functional class ≤ III
  • Optimal medical treatment

Exclusion Criteria

  • Contraindications for a maximal cardiopulmonary exercise testing (CPET) according to the American Thoracic Society/American College of Chest Physicians Statement
  • Moderate to severe COPD

Outcomes

Primary Outcomes

Aerobic exercise capacity

Time Frame: 3 months

Secondary Outcomes

  • Endothelial function, oxygen kinetics, ventilatory drive(3 months)

Study Sites (1)

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