Aerobic Interval Training Versus Combined Aerobic Interval Training and Strength Training Effects in Patients With Heart Failure
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Chronic Heart Failure
- Sponsor
- University of Athens
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Aerobic exercise capacity
- Last Updated
- 11 years ago
Overview
Brief Summary
Chronic heart failure (CHF) is a common syndrome characterized by several central hemodynamic and peripheral vascular and muscle abnormalities including autonomic imbalance, neuro-hormonal over-activation and decreased oxidative status.
In patients suffering from CHF, exercise confers several beneficial effects on the cardiovascular and peripheral systems, mainly by continuous aerobic training. However, interval aerobic training has also been validated as an alternate form of training that increases the exercise capacity of patients who are in CHF.
Recent studies have suggested that resistance training alone or as a complementary program besides the traditionally aerobic continuous training might exert favorable effects. However, little it is known about the combined effects of interval and strength training in CHF patients.
Aim of this prospective randomized controlled study was to investigate the effects of combined interval and strength training comparing to interval training alone in CHF patients.
Investigators
Serafim Nanas
MD
University of Athens
Eligibility Criteria
Inclusion Criteria
- •Stable systolic heart failure
- •NYHA functional class ≤ III
- •Optimal medical treatment
Exclusion Criteria
- •Contraindications for a maximal cardiopulmonary exercise testing (CPET) according to the American Thoracic Society/American College of Chest Physicians Statement
- •Moderate to severe COPD
Outcomes
Primary Outcomes
Aerobic exercise capacity
Time Frame: 3 months
Secondary Outcomes
- Endothelial function, oxygen kinetics, ventilatory drive(3 months)