KCT0003683
Recruiting
未知
The Efficacy and safety of Hwangryunhaedok-tang on Hangover and study of changes in gut microbiota composition
Pusan National University Korean Medicine Hospital0 sites40 target enrollmentTBD
ConditionsNot Applicable
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not Applicable
- Sponsor
- Pusan National University Korean Medicine Hospital
- Enrollment
- 40
- Status
- Recruiting
- Last Updated
- 7 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Healthy males between the ages of 19 and 39 who have experienced hangover after alcohol intake
- •2\. Subjects with body mass index \=18 and \<25kg/m2
- •3\. Subjects with the score of Alcohol Use Disorder Identification Test (AUDIT) \< 11
- •4\. Subjects who didn't drink within 7 days before recruitment
- •5\. Subjects who defecate once daily in average
- •6\. Subjects who signed on the written informed consent form and comply with study requirements after listening and fully understanding the details of this study.
Exclusion Criteria
- •1\. Subjects who have clinically significant diseases of hepatic, renal, respiratory, endocrine, genitourinary, cardiovascular, musculoskeletal system or hemato\-oncologic or psychiatric diseases or history of bellows
- •1\) uncontrolled diabetes or fast plasma glucose \= 126mg/dL or typical symptoms of diabetes mellitus (polyuria, polydipsia, unexplained body weight decrease), or plasma glucose \= 200 mg/dL at any time
- •2\) active renal disease or serum creatinine \= 1\.4 mg/dL
- •3\) active liver disease or alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels \= 60 IU/L
- •4\) uncontrolled hypertension or cardiac diseases of angina pectoris and myocardiac infarction
- •5\) experience of symptoms of cardiac diseases and severe toxicity after alcohol intake
- •6\) pancreatitis, gout, surgery of gastrointestinal tract
- •7\) taking anti\-ulcer drugs or treatment for gastric ulcer within 6 months
- •2\. Subjects with gastrointestinal diseases that can affect the absorption of test drug (Crohn's disease, ulcer, acute or chronic pancreatitis) or gastrointestinal surgery (not for simple appendectimy)
- •3\. Subjects with HBsAg (\+) or anti\-HCV ab (\+) or history of hepatitis B or C
Outcomes
Primary Outcomes
Not specified
Similar Trials
Recruiting
Not Applicable
The efficacy and safety of So-Cheong-Ryong-Tang for perennial allergic rhinitisKCT0002225Kyung Hee University154
Completed
Not Applicable
The effectiveness and safety of Hyeonggaeyeongyo-tang for chronic rhinitis according to pattern identification in Korean medicineKCT0001544Kyung Hee University40
Recruiting
Not Applicable
Effectiveness and safety of Maekmoondong-tang for chronic dry coughDiseases of th respiratory systemKCT0001646Kyung Hee University Oriental Medical Center58
Not yet recruiting
Not Applicable
Efficacy and Safety of Yukmijihwang-tang in the Treatment of Cough-Variant Asthma: Study Protocol for a Phase 2, Randomized, Double-blind, Placebo-controlled, Multicenter TrialKCT0006994Daejeon Korean Medicine Hospital of Daejeon University60
Completed
Not Applicable
Efficacy of Hwangryunhaedok-tang for patients with hyperlipidemiaKCT0004564Dunsan Korean Medicine Hospital of Daejeon University30