WAUTEAR trial

Phase 3

Recruiting

• Conditions: iver disease, or a healthy donor for living-donor liver transplantation.

• Registration Number: JPRN-jRCTs052220071
• Lead Sponsor: eno Masaki

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-08-09
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 250

Inclusion Criteria

(1) Age 20 years or older.
(2) ECOG Performance Status 0 to 2.
(3) Written consent provided.
(4) Scheduled to undergo (open/laparoscopic) liver resection due to liver disease, or to undergo liver resection as a donor for living-donor liver transplantation.
(5) Scheduled to undergo the following surgical procedures: right lobectomy, left lobectomy, right posterior sectionectomy, segment VII segmentectomy (for patients with liver disease) and right lobectomy, left lobectomy (for donors)

Exclusion Criteria

(1) Venous tumor thrombus (Vv2, 3).
(2) Biliary tumor thrombus (B3, 4).
(3) Needing biliary or vascular reconstruction.
(4) Dissection area overlaps with area of previous partial hepatectomy.
(5) Difficulty in taping hepatoduodenal ligament.
(6) Requiring resection of other organs except for gallbladder.
(7) BMI of 30 or more.
(8) Child-Pugh grade B or C.
(9) Platelet count <=10x104/micro-L.
(10) NYHA grade III or more.
(11) Implanted cardiac pacemaker or cardioverter defibrillator.
(12) Severe renal dysfunction (serum Cr >1.5 mg/dL).
(13) Severe respiratory dysfunction (forced expiratory volume in 1 second <1L or requiring rest because of shortness of breath during 100m or several minutes' walking).
(14) Other non-appropriate conditions, as determined by the principal investigator.

Study & Design

• Study Type: Interventional
• Study Design: Not specified