A study of immunity for chickenpox and measles in childhood cancer patients.
Phase 1
- Conditions
- This study will be conducted as a longitudinal study. Former studies have shown that immunity is affected after treatment against childhood cancer. We want to investigate humoral and cell-mediated immunity specifically targeted for varicella and measles, during and after treatment for childhood cancer. We also want to investigate vaccin response for varicella and measles.Therapeutic area: Diseases [C] - Cancer [C04]
- Registration Number
- EUCTR2019-004541-33-SE
- Lead Sponsor
- Västra Götalandsregionen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 160
Inclusion Criteria
• Children and young people (0-18.0 years) who start cancer treatment at the childhood cancer center in Gothenburg.
• Known vaccination status for measles and chickenpox before start of cancer treatment.
• Oral and written information for the study and signed consent form.
Are the trial subjects under 18? yes
Number of subjects for this age range: 160
F.1.2 Adults (18-64 years) no
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
•Known pre-existing primary immunodeficiency.
•Patients planned for relapse therapy or will undergo allogeneic stem cell transplantation (SCT).
•Known contraindication to any of the suggested vaccines.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method