Application of electroacupuncture combined with erector spinae plane block in anesthesia of non tracheal intubation thoracoscopic surgery

Phase 1

Recruiting

• Conditions: Thoracoscopic lobectomy

• Registration Number: ITMCTR2000003773
• Lead Sponsor: Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1) The ASA grade was I - III;
2) Aged 18-65 years, no gender limit;
3) Patients without previous immune system diseases;
4) Sign informed consent.

Exclusion Criteria

Study one exclusion criteria
1) Patients who have participated in other clinical trials in the past four weeks;
2) Patients who could not cooperate to complete the study included infectious diseases and other medical history;
3) Patients with positive urine pregnancy test;
4) Patients with preoperative pain, using central analgesics, opioid addicts and addicts;
5) Severe other system diseases and serious mental diseases were found before operation;
6) Patients with abnormal liver and kidney function (ALT, AST, BUN, Cr exceeding 1.5 times of normal value);
7) BMI>=30kg/m2 or Weight less than 50kg;
8) Organic heart disease or arrhythmia;
9) Emergency surgery or video-assisted thoracoscopic surgery;
10) Spinal deformity, abnormal blood coagulation, and infection of puncture site of erector spinalis plane block.
Study 2 exclusion criteria
1) Patients with skin infection at acupoints and limb nerve injury;
2) Patients who have participated in other clinical trials in the past four weeks;
3) Patients who could not cooperate to complete the study included infectious diseases and other medical history;
4) Patients with positive urine pregnancy test;
5) Patients with preoperative pain, using central analgesics, opioid addicts and addicts;
6) Severe other system diseases and serious mental diseases were found before operation;
7) Patients with abnormal liver and kidney function (ALT, AST, BUN, Cr exceeding 1.5 times of normal value);
8) BMI>=30kg/m2 or Weight less than 50kg;
9) Organic heart disease or arrhythmia;
10) Emergency surgery or video-assisted thoracoscopic surgery;
11) Spinal deformity, abnormal blood coagulation, and infection of puncture site of erector spinalis plane block.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intraoperative remifentanil dosage;Does the patient have agitation when extubation tracheal tube;Changes of vital signs at the beginning of skin incision;Whether or not to use remedial analgesics 2 hours after operation and VAS score;

Secondary Outcome Measures

Name	Time	Method
The highest value of partial pressure of carbon dioxide in blood gas analysis during operation;The changes of blood indexes such as plasma cortisol, pain mediators ß - endorphin, 5-hydroxytryptamine, inflammatory mediators IL-6 and TNF - a before and after operation;Time of spontaneous respiration recovery after anesthesia induction;Intraoperative remifentanil dosage;