Cardiac Rehabilitation for transient ischaemic Attack and Mild-Stroke: the CRAMS randomised controlled trial.

Not Applicable

Recruiting

• Conditions: transient ischaemic attack; stroke; Cardiovascular - Other cardiovascular diseases; Stroke - Ischaemic; Physical Medicine / Rehabilitation - Other physical medicine / rehabilitation

• Registration Number: ACTRN12621001586808
• Lead Sponsor: A/Prof Nicole Freene

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-11-19
• Last Update Posted: 14 November 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 140

Inclusion Criteria

Eligible participants must:
•be 18+ years old;
•have a documented transient ischaemic attack (TIA) or mild non-disabling ischaemic stroke within the previous 12 months (National Institutes of Health Stroke Scale (NIHSS) score 0-4);
•reside in the Australian Capital Territory.

Exclusion Criteria

Participants will be excluded if they have:
•evidence of intracranial haemorrhage on a CT or MRI study
•undergone recent (<30 days) carotid endarterectomy
•evidence of disabling stroke as measured by modified Rankin Scale score of greater than or equal to 3
•New York Heart Association class II-IV symptoms of heart failure
•uncontrolled arrhythmias
•severe chronic obstructive pulmonary disease
•uncontrolled hypertension
•symptomatic peripheral artery disease
•unstable angina
•uncontrolled diabetes
•do not have adequate English language skills, including significant speech impairment, or cognitive skills to agree to take part om the study or participate in a group exercise program (may be guided by formal testing of cognition such as the MMSE)
•previously completed cardiac rehabilitation.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Functional exercise capacity (6-minute walk test). The 6-minute walk test (6MWT) is a commonly used objective measure of functional exercise capacity in cardiac rehabilitation and stroke. The distance an individual is able to walk along a flat 25–30 m walkway over a 6-min period, with breaks as required, is recorded. The test is a self-paced, submaximal test of exercise capacity, and has been found to have a moderate-to-high reliability and validity. A change in distance of 34 m is considered a clinically meaningful change in people post stroke.[Baseline (start of CVR program), 6-weeks (primary timepoint, end of CVR program) and 6-months (follow-up).]