Preoperative Inspiratory Muscle Training Effects on the Perioperative Inflammatory Reaction in Cardiac Surgery.

Not Applicable

Completed

• Conditions: Prehabilitation; Respiratory Therapy; Thoracic Surgery
• Interventions: Other: Prehabilitation with inspiratory muscle training

• Registration Number: NCT03158402
• Lead Sponsor: University Hospital, Angers

Brief Summary

This study evaluates the impact of preoperative high-intensity inspiratory muscle training (IMThi) before cardiac surgery on perioperative inflammatory response. Half participants will receive high intensity inspiratory muscle training and the others a sham inspiratory muscle therapy.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-05-16
• Study First Submitted QC: 2017-05-16
• Study First Posted: 2017-05-18
• Study Start: 2018-02-14
• Primary Completion: 2019-06-12
• Study Completion: 2021-01-08
• Status Verified: 2023-01
• Last Update Submitted: 2023-01-16
• Last Update Posted: 2023-01-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Waiting for thoracic surgery with valve replacement
• Preoperative surgeon consultation between 3 and 6 weeks before surgery

Exclusion Criteria

• Patient with antecedent of lung surgery
• Patient with neuromuscular or neurovascular disease
• Non anticipated surgery with a time between surgeon consultation and surgery inferior to 3 weeks.
• Inhability to do the preoperative exercises

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
sham IMT	Prehabilitation with inspiratory muscle training	Preoperative Inspiratory muscle training at low intensity (15% Pimax) which is considered as a no effect training.
Hi Intensity IMT	Prehabilitation with inspiratory muscle training	High intensity muscle training in the preoperative period at 80% of the maximal inspiratory muscle pressure.

Primary Outcome Measures

Name	Time	Method
Preoperative STNFr1 level	Outcome is evaluated at the training initiation and re evaluated 24hours before the surgery	Post training and preoperative Serum concentration of the SRNFr1 cytokine.

Trial Locations

Locations (1)

University Hospital Angers; 🇫🇷 Angers, France