ACTRN12607000520437已完成1 期
A Phase 1, Two-Stage, Dose-Escalation Study of BNC105P, a Novel Vascular Disrupting Agent, in Patients with Advanced Solid Tumors
适应症
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 -2147483648 No limit（—）
- 性别
- All
入选标准
- •(i) Confirmed solid malignancy; (ii) Life-expectancy of greater than 12 weeks; (iii) No anticancer chemotherapy for the preceding 4 weeks; (iv) Adequate organ function; (v) Disease amenable to assessment by MRI; (vi) Adequate performance score (Eastern Cooperative Oncology Group score of 0-2)
排除标准
- •(i) Patients must not have received other experimental agents in preceding 4 weeks; (ii) Known brain disease; (iii) Patients with various cardiovascular risk factors are excluded; (iv) Pregnancy and immune deficiency; (v) Patients on full dose anticoagulants are excluded.
研究者
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