Effect of dexmedetomidine on haemodynamic changes in middle ear surgeries

Phase 2

• Conditions: Health Condition 1: O- Medical and SurgicalHealth Condition 2: H748- Other specified disorders of middle ear and mastoid

• Registration Number: CTRI/2023/09/057351
• Lead Sponsor: Jawaharlal Nehru Medical College

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 18 September 2023

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Patients of physical status I and II according to American Society of Anesthesiologists

(ASA) who are without comorbidities ,scheduled for elective middle ear surgery under

general anaesthesia.

Exclusion Criteria

Patients with severe obesity (body mass index greater than 35),

renal insufficiency (serum creatinine more than 1.6 mg/dl),

liver dysfunction (serum glutamic oxaloacetic transaminase/ serum glutamic pyruvic

transaminase values more than 50% of normal),

patients with difficult airways,

cardiorespiratory abnormalities (Diabetes, Hypertension, New York Heart Association

heart failure grades 3 and 4, obstructive and restrictive lung diseases),

, pregnant, currently breast feeding women,

history of sleep apnea planned / emergency surgeries in neck and oral cavity.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Infusion of Dexmedetomidine prior to endotracheal extubation will act on suppression of <br/ ><br>haemodynamic stress responseTimepoint: 30 minutes.

Secondary Outcome Measures

Name	Time	Method
ot applicableTimepoint: Not applicable