Use of Hyaluronic Acid Injection in Lateral Patellar Compression With Femoral Condylar Degenerative Changes After Arthroscopic Release

Not Applicable

Completed

• Conditions: Anterior Knee Pain Syndrome
• Interventions: Device: Hyaluronic acid injection; Device: No injection of Hyaluronic acid

• Registration Number: NCT04134611
• Lead Sponsor: Hawler Medical University

Brief Summary

Ninety patients are involved in this study, who underwent arthroscopic lateral patellar release for lateral patellar compression syndrome and they had patellofemoral degenerative lesion, which diagnoses by MRI preoperatively and proved by arthroscopic examination to be early stages of degenerative changes with no loss of articular surface. The patients were divided in to two groups (A and B). Group A (45 patients) were treated by local injection of Hyaluronic acid intraarticularly, and Group B (45 patients) were no injection intraarticular.

Detailed Description

This study was done by one orthopedic surgeon in two hospitals. Ninety patients are involved in this study, who underwent arthroscopic lateral patellar release for lateral patellar compression syndrome and they had patellofemoral degenerative lesion, which diagnoses by MRI preoperatively and proved by arthroscopic examination to be early stages of degenerative changes with no loss of articular surface. The patients were divided in to two matched groups (A and B) regarding the age and gender; Group A (45 patients) were treated by local injection of Hyaluronic acid intraarticularly, 2 weeks after arthroscopy and were followed by VAS of knee pain for one year at (3) months, (6) months and (12) months, and Group B (45 patients) were no injection intraarticular. The study started on June (2017) and ends on March (2020). injection of Hyaluronic acid was used and followed in the same way. All patients presented with anterior knee pain which failed to respond to conservative treatment for 6 weeks or recurrent of symptoms after stopping of conservative treatment which involved changes of life style and NSAID. MRI done for all patients before operation.

Study Timeline

• Study Start: 2017-06-01
• Study First Submitted: 2019-10-17
• Study First Submitted QC: 2019-10-18
• Study First Posted: 2019-10-22
• Primary Completion: 2020-03-10
• Study Completion: 2020-03-20
• Status Verified: 2020-06
• Last Update Submitted: 2020-06-08
• Last Update Posted: 2020-06-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

• Lateral patellar compression syndrome

Exclusion Criteria

• Patellar instability.
• Smoking.
• Diabetes Mellitus.
• Previous knee surgery.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Knee arthroscopy with Hyaluronic acid injection	Hyaluronic acid injection	Those patients who received hyaluronic acid injection
Knee arthroscopy without Hyaluronic acid injection	No injection of Hyaluronic acid	Knee arthroscopy who did not Hyaluronic acid injection

Primary Outcome Measures

Name	Time	Method
Visual analogue score of knee pain	The VAS for knee pain was measured 24 months after operation	Visual analogue score of knee pain describe knee pain from degree 0 where no pain to degree 10 where is severe pain
Kujala score	Preoperative assessment and 2 year postoperatively	Kujala score questionnaire up to 100

Trial Locations

Locations (1)

Sherwan Hamawandi; 🇮🇶 Erbil, Iraq