Comparative Effects of Tensioning and Sliding Neural Mobilization on Nerve Root Function :Randomized Controlled Trial
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- University of Sharjah
- Enrollment
- 90
- Locations
- 4
- Primary Endpoint
- Change in dermatomal somatosensory evoked potentials
Study Overview
Brief Summary
the current study will try to answer the question: Is it theoretically possible, that increased longitudinal stress on nerve root from sliding or tensioning intervention may subtly affect the neural function? Our hypothesis is that tensioning and sliding, differently affect the neural function.
Detailed Description
A prospective, parallel randomized, controlled study will be conducted at a research laboratory of our University. Participant recruitment will begin following approval from the Ethics Committee .The patients will participate in the study after signing an informed consent form prior to data collection.
Per inclusion criteria, subjects will be between 18 and 50 years of age, not currently experiencing any neck or dominant upper extremity symptoms, do not have a history significant for a chronic painful condition, and will not using pain relievers. Prior to participating in any study-related procedures, participants will read and signed an informed consent form approved by the Institutional Review Board.
Participants will be divided into three groups; One group will receive neural gliding mobilization and the other neural tensioning mobilization, both targeting the median nerve.
. the third group will receive sham neural mobilization intervention . Participants were not given information on which neural mobilization technique they were receiving; they were only told that they could receive one of two different neural mobilization techniques. Six sessions will be given every other day for 2 weeks.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Outcomes Assessor)
Masking Description
The participants as well as The assessor, who took the measurements for both the intervention and control groups, was blinded to the subject's group, while the treating therapist was not blinded to the treatment intervention.
Eligibility Criteria
- Ages
- 18 Years to 30 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •not currently experiencing any neck or dominant upper extremity symptoms.
- •do not have a history significant for a chronic painful condition.
- •do not using pain relievers.
Exclusion Criteria
- •inflammatory joint disease or other systemic pathologies.
- •prior history of overt injury and surgery relating to the musculoskeletal system.
- •disorder related to the spine and extremities.
- •musculoskeletal pain in the last three months.
Outcomes
Primary Outcomes
Change in dermatomal somatosensory evoked potentials
Time Frame: baseline (pre-treatment) , 2 weeks ,through study completion, an average of 1 week
In all dermatomes, 2 complete recording runs will be undertaken during each session with averages of 250 to 1200 cortical responses from scalp surface recording electrodes (C3'-C4' in a 10-20 electrode configuration) of the contralateral scalp to the stimulated dermatomes being stimulated. The impedance of ground and scalp electrodes will be maintained at \< 5 k Cutaneous areas of L3,L4,L5, S1 sensory roots will be stimulated in lower limb with the electrical impulses of 0.2 ms duration, frequency of 3.3 Hz and intensity 3 times higher than the sensory threshold will be determined individually for each subject.
Secondary Outcomes
- Change in Skin Sympathetic response(baseline (pre-treatment) , 2 weeks ,through study completion, an average of 1 week)
- Change in Pressure pain threshold(baseline (pre-treatment) , 2 weeks of treatment and at 1 week following the end of treatment)
Investigators
Ibrahim Moustafa
Associate professor-chair of Physiotherapy Department Affiliation: University of Sharjah
University of Sharjah