Sequelae of Developmental Dysplasia of the Hip

Active, not recruiting

• Conditions: Hip Dysplasia; Developmental Dysplasia of the Hip

• Registration Number: NCT02431871
• Lead Sponsor: University of Oulu

Brief Summary

The aim of this study is to assess long term effects of developmental dysplasia of the hip (DDH) to overall health and quality of life later in life. We compare hip radiographs, hip symptoms, clinical examination, head asymmetry, dental examination and intraoral scans of 170 children and young adults treated for DDH in their childhood with age and sex matched controls.

Detailed Description

Developmental dysplasia of the hip (DDH) is the most common musculoskeletal disorder in infancy. However there are few reports of long term effects of successfully treated DDH. Incidence of DDH in neonatal period is approximately 1-10/1000 depending on screening protocols used, the age of the infant during screening and which ultrasonographic findings are considered normal and which DDH. The prevalence of hip dysplasia in adult population is grossly 4 % when using Wibergs Centre-Edge (CE) ≤ 20° as definition of dysplasia. It is still unclear, what is the relation between adult acetabular dysplasia and developmental dysplasia in children. Hip dysplasia overall is a major contributing factor in hip osteoarthrosis and total hip replacement in young adults.

The aim of this study is to assess long term effects of developmental dysplasia of the hip to overall health and quality of life later in life. We compare hip radiographs, hip symptoms, clinical examination, head asymmetry, dental examination and intraoral scans of 170 children and young adults treated for DDH in their early childhood with age and sex matched controls.

Study Timeline

• Study First Submitted: 2015-04-20
• Study First Submitted QC: 2015-04-27
• Study First Posted: 2015-05-01
• Study Start: 2016-01
• Primary Completion: 2022-12
• Status Verified: 2023-11
• Last Update Submitted: 2023-11-27
• Last Update Posted: 2023-11-29
• Study Completion: 2026-12

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 340

Inclusion Criteria

Not provided

Exclusion Criteria

• neurological or developmental condition which can influence hip development such as cerebral palsy or spina bifida
• other significant congenital anomalies of musculoskeletal system such as club feet

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Wibergs Centre-Edge Angle	10 - 30 years after DDH has been treated	angle degree

Secondary Outcome Measures

Name	Time	Method
Presence of facial asymmetry	10 - 30 years after DDH has been treated	Determined by 3D -photogrammetric images
The Copenhagen Hip and Groin Outcome Score (HAGOS)	10 - 30 years after DDH has been treated	score in numbers
Oral Heath Impact Profile	10 - 30 years after DDH has been treated	Oral Heath Impact Profile (OHIP-14) -questionaire to assess Oral Health-related Quality of Life
Occlusal asymmetries	10 - 30 years after DDH has been treated	Determined by dental examination and intraoral scan

Trial Locations

Locations (1)

University of Oulu; Oulu University Hospital; 🇫🇮 Oulu, Finland