MedPath

Effect of probiotic Bacillus clausii UBBC07 in children with Acute Diarrhoea

Phase 4
Completed
Conditions
Health Condition 1: null- Acute Diarrhoea
Registration Number
CTRI/2017/08/009543
Lead Sponsor
nique Biotech Ltd
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
119
Inclusion Criteria

1.Children aged between >=6 months and <=5 years

2.Subjects with clinical diagnosis of acute

diarrhoea.

3.Subjects who experienced more than 3 loose stools in the last 24 hours

4.Subjects with no major illness.

5.Parents of the subjects willing to give written informed Consent & willing to follow study procedures.

6.Informed Consent form signed by the subjectâ??s parent/Legally Acceptable Representative or an impartial witness

Exclusion Criteria

1.Children with severe malnutrition (weight for height < 3 SD of WHO charts).

2.Subjects requiring antibiotics during the study period.

3.Presence of severe diarrhoea which, in the opinion of the investigator, requires treatment other than investigational product and ORS.

4. Presence of visible blood in the stool.

5.Use of probiotics in the previous three weeks, use of antibiotics or any antidiarrhoeal medication in the previous three weeks.

6.Participated in any clinical trial or used any investigational product in the past 90 days.

7.Known or expected hypersensitivity to any of the active substances or excipients.

8.Previous use (within 48 hours) of kaolin, pectin, bismuth subsalicylate, racecadotril, loperamide, atropine and other anticholinergic agents

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath