A clinical trial to study the effects of two drugs, metformin lotion and zinc oxide cream in patients with melasma, a type of facial pigmentatio
- Conditions
- Health Condition 1: L811- Chloasma
- Registration Number
- CTRI/2023/09/057901
- Lead Sponsor
- ITHYAMS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Patients of both genders above 18 years who were clinically diagnosed to have melasma
2.Patients willing to give a written informed consent
Before starting the study
1.Pregnant & lactating mothers
2.Patients on oral contraceptives, phenytoin
3.Patients with unrealistic expectations
4.Patients who are allergic to metformin
5.Patients on medications for melasma since at least 2 weeks for topical therapy, 1 month for systemic steroids, 3 months for cosmetic procedures such as laser, dermabrasion, or peels
6.Patients with co-morbidities-DM, SHTN, TB,CAD,EPILEPSY,BA, carcinomas, Renal dysfunction,
During Study
1.If patient develops side effects during the treatment
2.If patient wants alternate treatment during the study.
3.If patient wants to discontinue the treatment.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction in intensity of pigmentationTimepoint: 8 weeks after using medication
- Secondary Outcome Measures
Name Time Method Prevention of relapseTimepoint: 1 year