Tools to Assess Medication Adherence

• Conditions: Medication Adherence
• Interventions: Other: Measure of medication adherence

• Registration Number: NCT04772066
• Lead Sponsor: University Hospital, Montpellier

Brief Summary

The issue of medication adherence (MA) has long been undestimated but is now growing interest due to both the increase of patients with chronic diseases and the aging of the population. According to the World Health Organization, only 50% of patients with chronic illnesses correctly follow physician's prescriptions in developed countries. Beyond the individual consequences that failure to adherence can engender (increased morbidity, mortality and hospitalizations), this concept also encompasses a collective dimension (risk of transmission of infectious diseases and increased health care costs). Today, improving MA would have more impact on human health than developping new medical therapies. That's why detecting non-adherence constitutes a major public health issue in which pharmacists play a significant role through medication reconciliation and patients' education.

The methods wildly used are based on indirect measurement: questionnaires completed by the patient himself or the Medication Possession Ratio (MPR). Each method has its own advantages and disadvantages, but none is considered as the gold standard. The Montpellier University Hospital set up a MA self-report scale ranging from 0 (low) to 10 (high adherence) in the various care units where the clinical pharmacy activity is deployed.

The purpose of this study was to assess the MA according to this numerical scale and the MPR calculation, and evaluate the correlation between these two methods.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-11-01
• Status Verified: 2021-02
• Study First Submitted: 2021-02-23
• Study First Submitted QC: 2021-02-23
• Study First Posted: 2021-02-26
• Last Update Submitted: 2021-03-05
• Last Update Posted: 2021-03-08
• Primary Completion: 2021-12-01
• Study Completion: 2021-12-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 600

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Non adherent patients	Measure of medication adherence	Non adherent patients
Adherent patients	Measure of medication adherence	Adherent patients

Primary Outcome Measures

Name	Time	Method
MA according to Medication Possession Ratio (MPR) calculation	1 day	MA according to Medication Possession Ratio (MPR) calculation
Self-reported MA according to self-reported medication adherence scale	1 day	Self-reported MA according to self-reported MA scale : The self-report scale ranges from 0 (low) to 10 (high adherence)

Secondary Outcome Measures

Name	Time	Method
Variables associated with medication non-adherence	1 day	Variables associated with medication non-adherence
Number of patients with medication non-adherence according to self-reported MA scale and MPR calculation	1 day	Number of patients with medication non-adherence according to self-reported MA scale and MPR calculation

Trial Locations

Locations (1)

Uhmontpellier; 🇫🇷 Montpellier, France