MedPath

Peritoneal Carcinomatosis Extent Evaluation: Radiologic, Laparoscopic and Pathologic.

Conditions
Peritoneal Carcinomatosis
Registration Number
NCT03798132
Lead Sponsor
Shimaa Abdalla Ahmed
Brief Summary

pathologically proved ovarian cancer patients that underwent contrast enhanced abdomino-pelvic CT and diagnostic laparoscopy before cytoreductive surgery (CRS) will be included in the study. Calculation of PCI (peritoneal cancer index) using Sugarbaker's method, peritoneal carcinomatosis extent will be categorized into low, moderate and large. Agreement in general and in each category between CT, laparoscopy, surgery and pathology will be assessed using kappa agreement.

Detailed Description

we will search medical records of primary ovarian cancer patients underwent CT abdomen, laparoscopy followed by cytoreductive surgery to calculate peritoneal carcinomatosis extent by each modality.

Regional PCI was calculated in each of the 13 anatomical abdominopelvic regions, then total PCI by summation of the lesion size score, it ranged from 0 to 39. Categorization of peritoneal carcinomatosis was classified into 3 categories low if PCI \< 10, moderate if 10-20, and large if \>20.

Recruitment & Eligibility

Status
UNKNOWN
Sex
Female
Target Recruitment
80
Inclusion Criteria

pathologically proved ovarian cancer patients underwent contrast enhanced abdominopelvic CT and diagnostic laparoscopy before cytoreductive surgery -

Exclusion Criteria

recurrent ovarian cancer

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
peritoneal carcinomatosisone year

Agreement in general and in each category between CT, laparoscopy, surgery and pathology was assessed using kappa agreement.

Secondary Outcome Measures
NameTimeMethod
surgical decision making.one year

correlation of peritoneal carcinomatosis categorization with surgical decision

Trial Locations

Locations (1)

South Egypt Cancer Institute

🇪🇬

Assiut, Egypt

© Copyright 2025. All Rights Reserved by MedPath