ISRCTN36646813
Completed
未知
Early treatment of idiopathic Parkinson's disease with dopaminergic agonist piribedil in monotherapy. A two-year randomised, parallel, placebo-controlled study in idiopathic Parkinsonian de novo patients
Institut de Recherches Internationales Servier (France)0 sites400 target enrollmentMarch 31, 2006
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Institut de Recherches Internationales Servier (France)
- Enrollment
- 400
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Out\-patients between 30 to 77 years old, with stage 1 to 3 (Hoehn and Yahr) and less than six weeks of previous L\-dopa treatment, with less than 3 months of previous treatment by a dopaminergic agonist
Exclusion Criteria
- •1\. Patients frequently falling according to unified Parkinson's disease rating scale (UPDRS) II and/or III
- •2\. Prior experience of a dopaminergic complication
- •3\. Prior neurosurgery for PD
- •4\. Previous history of freezing
- •5\. Suspected autosomal juvenile Parkinsonism
- •6\. Atypical Parkinsonian symtoms caused by drugs, metabolic disorders or encephalitis
- •7\. History of psychotic symptoms
- •8\. Poor cognitive performance
Outcomes
Primary Outcomes
Not specified
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