The Incidence of Hypocalcemia in Pregnant Women at Siriraj Hospital
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 444
- 试验地点
- 1
- 主要终点
- The incidence of hypocalcemia in pregnant women at Siriraj Hospital
研究概览
简要总结
Calcium is an essential element for fundamental physiological functions and during pregnancy. However, higher calcium intake can induce constipation, flatulence, nausea, or kidney stones. This study aims to evaluate the incidence of hypocalcemia among pregnant women in the first half of pregnancy in Thailand. Also, Comparison of calcium level in pregnant women in the third trimester who received and not received calcium during pregnancy.
详细描述
The primary outcome is the incidence of hypocalcemia among pregnant women in the first half of pregnancy. This study also has secondary objectives. The one is associating factors with calcium level. After getting the results of maternal calcium level, the normal calcium level group will be divided into 2 groups for receiving calcium 1 g/day and no receiving calcium supplement. Another with hypocalcemia group will be decided into 2 groups for receiving calcium 1 g/day and 2 g/day. The calcium level was collected again in the third trimester.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Pregnant women who attend antenatal care clinic in Siriraj Hospital
- •Pregnant women with gestation less than 20 weeks of gestation
- •Singleton pregnancy
排除标准
- •Pregnant women who has underlying diseases including liver disease and vitamin D deficiency
- •Pregnant women are malnutrition patients
- •Pregnant women who receive calcium supplement before enrollment
研究组 & 干预措施
Normal calcium level with receiving calcium supplement 1g/day
Pregnant women with normal calcium level in the first half of pregnancy receive calcium supplement 1g/day.
干预措施: Calcium supplement (Drug)
Hypocalcemia with receiving calcium supplement 1g/day
Pregnant women with hypocalcemia in the first half of pregnancy receive calcium supplement 1g/day.
干预措施: Calcium supplement (Drug)
Hypocalcemia level with receiving calcium supplement 2g/day
Pregnant women with hypocalcemia in the first half of pregnancy receive calcium supplement 2g/day.
干预措施: Calcium supplement (Drug)
结局指标
主要结局
The incidence of hypocalcemia in pregnant women at Siriraj Hospital
时间窗: 1.5 year
The incidence of hypocalcemia in pregnant women in the first half of pregnancy. Material blood will be taken for calcium level. The hypocalcemia is defined as total calcium level less than 8.5 mg/dl.
次要结局
- The demographic and pregnant factors are associating with maternal calcium level in the first half of pregnancy assessed by the questionnaire and scrupulous chart review(1.5 year)
- The calcium level in pregnant women in the third trimester(2 year)
研究者
Tachjaree Panchalee
Assistant Professor Tachjaree Panchalee
Siriraj Hospital