The Incidence of Hypocalcemia in Pregnant Women at Siriraj Hospital
Overview
- Phase
- Not Applicable
- Intervention
- Calcium supplement
- Conditions
- Hypocalcemia in Pregnancy
- Sponsor
- Siriraj Hospital
- Enrollment
- 444
- Locations
- 1
- Primary Endpoint
- The incidence of hypocalcemia in pregnant women at Siriraj Hospital
- Status
- Active, not recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Calcium is an essential element for fundamental physiological functions and during pregnancy. However, higher calcium intake can induce constipation, flatulence, nausea, or kidney stones. This study aims to evaluate the incidence of hypocalcemia among pregnant women in the first half of pregnancy in Thailand. Also, Comparison of calcium level in pregnant women in the third trimester who received and not received calcium during pregnancy.
Detailed Description
The primary outcome is the incidence of hypocalcemia among pregnant women in the first half of pregnancy. This study also has secondary objectives. The one is associating factors with calcium level. After getting the results of maternal calcium level, the normal calcium level group will be divided into 2 groups for receiving calcium 1 g/day and no receiving calcium supplement. Another with hypocalcemia group will be decided into 2 groups for receiving calcium 1 g/day and 2 g/day. The calcium level was collected again in the third trimester.
Investigators
Tachjaree Panchalee
Assistant Professor Tachjaree Panchalee
Siriraj Hospital
Eligibility Criteria
Inclusion Criteria
- •Pregnant women who attend antenatal care clinic in Siriraj Hospital
- •Pregnant women with gestation less than 20 weeks of gestation
- •Singleton pregnancy
Exclusion Criteria
- •Pregnant women who has underlying diseases including liver disease and vitamin D deficiency
- •Pregnant women are malnutrition patients
- •Pregnant women who receive calcium supplement before enrollment
Arms & Interventions
Normal calcium level with receiving calcium supplement 1g/day
Pregnant women with normal calcium level in the first half of pregnancy receive calcium supplement 1g/day.
Intervention: Calcium supplement
Hypocalcemia with receiving calcium supplement 1g/day
Pregnant women with hypocalcemia in the first half of pregnancy receive calcium supplement 1g/day.
Intervention: Calcium supplement
Hypocalcemia level with receiving calcium supplement 2g/day
Pregnant women with hypocalcemia in the first half of pregnancy receive calcium supplement 2g/day.
Intervention: Calcium supplement
Outcomes
Primary Outcomes
The incidence of hypocalcemia in pregnant women at Siriraj Hospital
Time Frame: 1.5 year
The incidence of hypocalcemia in pregnant women in the first half of pregnancy. Material blood will be taken for calcium level. The hypocalcemia is defined as total calcium level less than 8.5 mg/dl.
Secondary Outcomes
- The demographic and pregnant factors are associating with maternal calcium level in the first half of pregnancy assessed by the questionnaire and scrupulous chart review(1.5 year)
- The calcium level in pregnant women in the third trimester(2 year)