Comparisons of healthy sleep education alone and combined with pharmacotherapy in the treatment of sleep disturbances in Non-psychotic depressed patients

Sleep disturbances are nearly universal in psychiatric disorders, especially mood disorders. Research investigating associations between sleep and affective illness has largely focused on depression. This study evaluated the efficacy of lorazepam and Sleep hygiene education, alone or in combination on sleep in patients with non-psychotic depression. One hundred twenty patients with non-psychotic depression were randomly divided into 3 groups and either received Sleep hygiene education (n = 40), lorazepam (n = 40) and combined (n = 40) who were admitted to Farshchian hospital in Hamadan, Iran. The intervention lasted for 8 weeks. Pittsburgh Sleep Quality Index (PSQI) was used to measure of overall sleep quality. ANCOVA including and MANOVA were used to test intra-group and inter-group differences. Result showed that Sleep hygiene education, lorazepam and combined intervention were significant effect on sleep in patients with non-psychotic depression. There was no significant difference between Sleep hygiene educations and lorazepam. But found that intervention with a combination of Sleep hygiene educations and lorazepam had significant advantages over intervention with lorazepam or Sleep hygiene education alone (P