Assessment of atherosclerotic risk, in young, non-obese women with female pattern hair loss

Androgenetic alopecia (AGA) in women, also commonlyknown as Female pattern hair loss (FPHL) is a nonscarring progressive thinningof hair, particularly in the frontal, central, and parietal scalp, as a resultof follicular miniaturisation. Numerous studies have demonstratedthe unavoidable connection between androgenetic alopecia in males and coronaryartery disease. However, a paucity of similar studies in womencalls for the need to know a similar association.

Corelating, different grades of FPHL with the severityof atherosclerosis in healthy, young, non-obese women, would help in isolatingwomen who are prone to developing coronary artery disease (CAD). There isabundance of evidence to prove the relationship between concentrations oflipids and lipoproteins with the development of CAD leading to ischaemic heartdisease. It has been demonstrated that estimating the atherogenic index, or thelog of the ratio of triglycerides to high-density lipoproteins (HDL), is asuperior predictor of cardiovascular events.

Numerous circulating markers of inflammation have beenstudied for their potential to forecast the risk of vascular events becausethere is a wealth of evidence linking inflammation to atherosclerosis and acutecoronary syndromes (ACS). The biomarker that is most researched in this contextis C-reactive protein. It is a prognostic indicator for cardiovascularmortality and recurrence for both primary and secondary protection.

Additionally, estimation of Epicardial Adipose Tissue (EAT)Thickness provides a major indicator of atherosclerosis linked tocardiovascular risk factors and outcomes.

This study wouldhelp in identifying young women who otherwise do not have any disease and arestill prone to developing CAD. Diagnosing FPHL and correlating it withatherogenic potential would be a non-invasive way to diagnose CAD earlier.