Efficacy of oral supplement omega-3 in treatment of recurrent aphthous stomatitis
- Conditions
- Recurrent Aphtous Stomatitis.Recurrent oral aphthae
- Registration Number
- IRCT20160112025986N3
- Lead Sponsor
- Babol University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
both male and female with older than18 years of age
having recurrent minor aphthous ulcer for at least 1 year with a frequency of at least 1 outbreak per month
presenting with 1 to 3 aphthous ulcers (of less than 48 hours’ duration) with a size no greater than10 mm in diameter
withoutanesthesia or paresthesia
individuals who had concurrent clinical conditions that could pose a health risk to the participants,including serious heart, liver, or kidneydys functions
pregnancy or lactation
ulcers as a manifestationof systemic disorders such as ulcerative colitis, Crohn disease, Behçet syndrome, or serious anemia
use of medications such as systemic steroids,immunomodulatory agents, antibiotics, or nonsteroidalanti-inflammatory drugs within 1 month before study entry
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method umber of aphtous ulcer. Timepoint: First appointment; monthly for 6 months. Method of measurement: Count the ulcers.;Level of pain. Timepoint: First appointment, monthly for 6 months. Method of measurement: Visual Analogue Scale (VAS ).;Average duration of ulcer episodes. Timepoint: First appointment; monthly for 6 months. Method of measurement: Number of days.;The average score of COMDQ. Timepoint: First appointment; 6 month later. Method of measurement: Filling the questionnaire.
- Secondary Outcome Measures
Name Time Method