Is Size of Cisterna Magna Related to the Fetal Gender and Gestational Age

Completed

• Conditions: Size of Cisterna Magna; Gestational Age and Gender Conditions
• Interventions: Behavioral: ultrasound observation

• Registration Number: NCT06139978
• Lead Sponsor: Assiut University

Brief Summary

The cisterna magna (CM) is a large subarachnoid cerebrospinal space that lies between the caudal aspect ofthe cerebellum and the medulla oblongata, drainingthe fourth ventricle . The evaluation of the fetal cisterna magna is animportant part of obstetric ultrasound which targetsdetection of prenatal malformation of the fetal centralnervous system (CNS).Therefore, measuring the size ofthe cisterna magna has important clinical significancefor diagnosing fetal nervous system abnormalities.

Studies about the relationship between the anteroposterior diameter of the CM and the gestational age (GA) are still controversial. Some articles havepointed out that there was a good correlationbetween the diameter of the CM and GA

Detailed Description

Prospective study that will include pregnant women who are between 20 weeks 0 days and 39 weeks 6 days of gestation. As in cross sectional study each fetus is considered only once. with use of magnetic resonance ultrasonography.( ultrasonography is a noninvasive imaging test uses high-frequency sound waves to create real-time pictures or video of internal organs or other soft tissues)

Study Timeline

• Study First Submitted: 2023-11-15
• Study First Submitted QC: 2023-11-15
• Study First Posted: 2023-11-18
• Study Start: 2023-12-01
• Primary Completion: 2024-12-01
• Study Completion: 2024-12-30
• Status Verified: 2025-01
• Last Update Submitted: 2025-01-28
• Last Update Posted: 2025-01-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 450

Inclusion Criteria

• Pregnant women who are between 20 weeks 0 days and 39 weeks 6 days of gestation.
• Singleton pregnancy.

Exclusion Criteria

.gestational age can not be confirmed.

• Fetal malformations or intrauterine growthretardation
• Women with chronic diseases.
• bodymass index >30

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Pregnant women in male fetus	ultrasound observation	-
Pregnant women in female fetus	ultrasound observation	-

Primary Outcome Measures

Name	Time	Method
Correlation of cisterna magna size to the gender and gestational age	48 months	Mesurment of anteroposterior diameter of cisterna magna by centimeters using 2D US

Trial Locations

Locations (1)

Assiut Medical School; 🇪🇬 Assiut, Egypt