In controlled hypertensive patients undergoing elective surgery, which of the three agents- propofol, thiopentone and etomidate (all the three are intravenous anaesthetic induction agents) , results in the most haemodynamically stable conditions during anaesthetic induction and intubation ?
- Conditions
- Health Condition 1: I10- Essential (primary) hypertension
- Registration Number
- CTRI/2018/02/012154
- Lead Sponsor
- VMMC and Safdarjung Hospital Delhi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 120
Adult ASA Physical status 2 patients, of either sex, scheduled for elective surgery, on regular and compliant anti-hypertensive treatment, labelled as controlled with not a single BP reading of >140/90 mm Hg within the past 7 days.
1. Co-morbid conditions like diabetes, epilepsy, chronic obstructive pulmonary disease, known adrenal insufficiency, obstetric, cervical spine surgery patients, a history of MI/ stroke/ renal failure.
2. Known sensitivity to propofol/ thiopentone/ etomidate/ opioids/ barbiturates/ egg/ soyabean and history of use of propofol/ thiopental/ etomidate within 1 week pre-operatively.
3. Anticipated difficult airway ( Modified Mallampati Grade III and IV ) and obese patients who have BMI of and above 30 kg/metre2.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method