Retrospective Cohort Study on Adjuvant Treatment of Coronary Heart Disease Angina Pectoris With Chinese Patent Medicine
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 12,400
- Locations
- 1
- Primary Endpoint
- Clinical biochemical indicators test
Study Overview
Brief Summary
A retrospective cohort study was performed in patients with angina pectoris who were treated with oral Chinese patent medicine and Western medicine.The hospital's medical record management system was used to collect symptoms of angina pectoris, dose and frequency of nitroglycerin use, clinical biochemical test and imaging examination.To explore the clinical efficacy of Chinese patent medicine in the treatment of coronary heart disease with angina pectoris, and provide reliable data support for its clinical application.
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Retrospective
Eligibility Criteria
- Ages
- 35 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Age 35-75 years old, gender is not limited;
- •Admission time is September 1, 2014 - September 1, 1919;
- •Patients with coronary heart disease and angina pectoris in the Department of Cardiology or Outpatient Department, the diagnosis of angina pectoris meets the diagnostic criteria of Western medicine and the standard of TCM syndrome differentiation;
- •Patients who met the criteria for drug treatment, the exposed group was treated with traditional Chinese medicine combined with Western medicine, and the non-exposed group was treated with Western medicine alone.
Exclusion Criteria
- •Combined with other heart diseases, neurosis, menopausal syndrome, hyperthyroidism, cervical or vertebral artery type cervical spondylosis, gastro-oesophageal reflux disease or esophageal hiatus hernia may cause chest pain;
- •patients with acute myocardial infarction, heart failure, myocarditis, cardiomyopathy, severe heart valve disease, liver failure or renal failure, malignant tumors and severe metabolic diseases, as well as patients with severe symptoms and uncontrollable angina;
- •Pregnant women, lactating women or women of childbearing age who have birth requirements;
- •Mental patients, or cognitive dysfunction;
- •The investigator believes that there are other situations that are not suitable for the trial.
Arms & Interventions
Exposed group
Chinese patent medicine combined with western medicine routine treatment
Intervention: Chinese patent medicine (Drug)
Outcomes
Primary Outcomes
Clinical biochemical indicators test
Time Frame: one year
Film degree exam
Time Frame: one year
Symptoms of angina
Time Frame: one year
Dosage and frequency of use of nitroglycerin
Time Frame: one year
Secondary Outcomes
No secondary outcomes reported
Investigators
Chunquan Yu
Director
Tianjin University of Traditional Chinese Medicine