NCT03925714招募中3 期
Investigating the Impact of p53 and SIRT1 in the Development of Type 2 DM Through the Treatment of Prediabetic Individuals by Either Nigetella Salivata or Metformin
Sherief Abd-Elsalam1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2019年4月1日最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Number of patients with improved insulin resistance
研究概览
简要总结
Investigating the impact of p53 and SIRT1 in the development of type 2 DM
详细描述
Investigating the impact of p53 and SIRT1 in the development of type 2 DM through the treatment of prediabetic individuals by either nigetella salivata or Metformin
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Prediabetic subjects.
排除标准
- •Confirmed diabetes.
- •Hepatic or renal impairment.
研究组 & 干预措施
life style
Other
life style control only
干预措施: life style (Other)
Metformin
Active Comparator
Metformin 500 mg twice daily
干预措施: Metformin (Drug)
Nigetella salivata
Experimental
NS 450 mg twice daily
干预措施: Nigetella salivata (Drug)
结局指标
主要结局
Number of patients with improved insulin resistance
时间窗: 6 months
Number of patients showing improved insulin resistance
次要结局
未报告次要终点
研究者
Sherief Abd-Elsalam
Ass. Prof. Tropical Medicine
Tanta University
研究点 (1)
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