COG-UK Project Hospital-Onset COVID-19 Infections (HOCI) Study: How effective are infection prevention and control measures that are informed by genetic analysis of coronavirus (rapid and standard) at preventing COVID-19 in NHS hospitals?

Not Applicable

Completed

• Conditions: Hospital-onset COVID-19 (SARS-CoV-2 infection); Infections and Infestations

• Registration Number: ISRCTN50212645
• Lead Sponsor: niversity College London

Brief Summary

2022 Protocol article in http://dx.doi.org/10.1136/bmjopen-2021-052514 (added 12/08/2022) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/36098502/ (added 27/09/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-05-20
• Study Completion: 2021-07-31
• Last Update Posted: 10 October 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 2170

Inclusion Criteria

Current inclusion criteria as of 14/04/2021:
1. Participants must have confirmed COVID-19 infection and be a hospital-onset COVID-19 infection (HOCI)
2. Participants must have provided nasal swab/pharyngeal swab/combined nasal and pharyngeal swab/nasopharyngeal aspirate or bronchoalveolar lavage sample for evaluation in the COG-UK project.
3. Participants may be of any age or gender to be included in the study. For clarity, in the above criterion a potential HOCI is an admitted patient at site with first confirmed test for COVID-19 >48 h after admission, where they were not suspected to have COVID-19 at time of admission

Previous inclusion criteria:
1. Participants must have confirmed COVID-19 infection and either:
1.1. Be a potential hospital-onset COVID-19 infection (HOCI), or
1.2. Potential workplace infection with SARS CoV-2 for site-based healthcare workers
2. Participants must have provided nasal swab/pharyngeal swab/combined nasal and pharyngeal swab/nasopharyngeal aspirate or bronchoalveolar lavage sample for evaluation in the COG-UK project.
3. Participants may be of any age or gender to be included in the study. For clarity, in the above criterion a potential HOCI is an admitted patient at site with first confirmed test for COVID-19 >48 h after admission, where they were not suspected to have COVID-19 at time of admission

Exclusion Criteria

Does not meet inclusion criteria

Study & Design

• Study Type: Interventional
• Study Design: Not specified