Clinical Study of Novel Diagnostic Techniques for Knee Osteoarthritis

Completed

• Conditions: Knee Osteoarthritis; Knee Injuries
• Interventions: Other: Intra-articular ultrasound imaging of knee joint during arthroscopy; Other: Non-invasive ultrasound imaging of knee; Other: Quantitative MRI imaging of knee; Other: Contrast-enhanced CT imaging of knee

• Registration Number: NCT01359553
• Lead Sponsor: University of Oulu

Brief Summary

The purpose of this study is to clarify the potential of intra-articular ultrasound imaging, non-invasive ultrasound imaging, quantitative MRI imaging, contrast-enhanced CT imaging and arthroscopy for diagnostics of knee osteoarthritis. All methods will be cross-correlated and compared with the arthroscopic findings.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-05
• Study First Submitted: 2011-05-22
• Study First Submitted QC: 2011-05-22
• Study First Posted: 2011-05-24
• Primary Completion: 2014-04
• Study Completion: 2014-05
• Status Verified: 2016-10
• Last Update Submitted: 2016-10-24
• Last Update Posted: 2016-10-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• Kellgren-Lawrence grade = 1-3 or cartilage defect detected in MRI
• Age >= 20 years

Exclusion Criteria

• Tumor or inflammation in the knee
• Severe general diseases
• Diabetes

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Knee pain	Quantitative MRI imaging of knee	Group with knee pain problems referred to an arthroscopy.
Knee pain	Intra-articular ultrasound imaging of knee joint during arthroscopy	Group with knee pain problems referred to an arthroscopy.
Knee pain	Non-invasive ultrasound imaging of knee	Group with knee pain problems referred to an arthroscopy.
Knee pain	Contrast-enhanced CT imaging of knee	Group with knee pain problems referred to an arthroscopy.

Primary Outcome Measures

Name	Time	Method
Arthroscopical OA grade	2014

Trial Locations

Locations (1)

Oulu University Hospital; 🇫🇮 Oulu, Finland