Effects of treatment with vitamin D3 in Hashimoto's Thyroiditis with vitamin D deficiency on Thyroid function, antithyroid antibodies and metabolic markers

Phase 2

• Conditions: Hashimoto's thyroiditis.; Autoimmune thyroiditis: Hashimoto's thyroiditis, Temporary hashitoxicosis, Lymphadenoid thyroiditis, Lymphocytic thyroiditis, Lymphomatosis Stroma

• Registration Number: IRCT2014120520216N1
• Lead Sponsor: Vice Chancellor for research, Isfahan University of Medical Science

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

age 20 to 60 years;
anti thyroid peroxidase antibody positive;
serum 25 hydroxyl vitamin D 3 is less than 20 nanogram per milliliter;
euthyroid or hypothyroid;
if Levothyroxin or other metabolic drugs like Statins, Metformin consumed, starting time was more than 6 months ago.
Exclusion criteria:
immunosuppressor drugs intake before the study;
dietary supplementation intake per oral or injections before study;
comorbid disease ;
severe weight loss;
insulin taking.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
25, hydroxyl vitamin D3. Timepoint: before entering to the study & 12 weeks after drug or placebo consumption. Method of measurement: serum level measurement.;TPOAb. Timepoint: before entering to the study & 12 weeks after drug or placebo consumption. Method of measurement: serum level measurement.;Thyroid Stimulating Hormone (TSH). Timepoint: before entering to the study & 12 weeks after drug or placebo consumption. Method of measurement: serum level measurement.

Secondary Outcome Measures

Name	Time	Method
Calcium. Timepoint: before entering to the study & 12 weeks after drug or placebo consumption. Method of measurement: serum level measurement.;PTH. Timepoint: before entering to the study & 12 weeks after drug or placebo consumption. Method of measurement: serum level measurement.