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Comparison of fasting glucose and oral glucose tolerance testing to screen for diabetes mellitus in subjects on long-term glucocorticoid therapy

Not Applicable
Completed
Conditions
Risk of diabetes in subjects receiving long-term glucocorticoid therapy
Metabolic and Endocrine - Diabetes
Registration Number
ACTRN12607000540415
Lead Sponsor
Repatriation General Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
150
Inclusion Criteria

Long-term glucocorticoid therapy (> 6 months)

Exclusion Criteria

Type 1 diabetes mellitus
Active inflammatory disease (defined as clinical evidence of active synovitis, elevated C-reactive protein (CRP) or recent intensification of immunosuppressive therapy)
Significant hepatic (AST or ALT > 3 times upper limit of normal) or renal (serum creatinine > 200µmol/L) dysfunction

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Sensitivity of fasting glucose to determine diabetes[At the end of the 12 month study period.]
Secondary Outcome Measures
NameTimeMethod
Prevalence of diabetes[At the end of the 12 month study period.]
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