NCT06272708
Recruiting
Not Applicable
Preliminary Exploration of Thromboelastography in the Monitoring of Anticoagulation in Maintenance Hemodialysis Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Thromboelastography
- Sponsor
- RenJi Hospital
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- thromboelastography parameter R value
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Objectives: To investigate the role of thromboelastography parameters (R, K, Angle, MA) in monitoring anticoagulation in maintenance hemodialysis (MHD) patients.
Subjects: Two hundred stable MHD patients. Methods: An observational study. Primary outcome: Relationship between thromboelastography parameter R Value and coagulation of hemodialysis circuit and dialyzer.
Secondary outcome: Relationship between thromboelastography parameters (K Value, Angle and MA) and coagulation of hemodialysis circuit and dialyzer.
Investigators
Renhua Lu
Chief Physician
RenJi Hospital
Eligibility Criteria
Inclusion Criteria
- •male or female patients aged over 18 years
- •stable patients undergoing maintenance hemodialysis treatment for at least 3 months
- •signed informed consent form
Exclusion Criteria
- •concomitant with severe diseases such as active malignancy, severe liver diseases, systemic infection, etc.
- •planned or ongoing pregnancy or lactation
- •unsuitable for inclusion in this study after assessment
Outcomes
Primary Outcomes
thromboelastography parameter R value
Time Frame: 2 hours after hemodialysis began
Relationship between thromboelastography parameter R value and coagulation of hemodialysis circuit and dialyzer
Secondary Outcomes
- thromboelastography parameter MA(2 hours after hemodialysis began)
- thromboelastography parameter K value(2 hours after hemodialysis began)
- thromboelastography parameter Angle(2 hours after hemodialysis began)
Study Sites (1)
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