NCT07457372WithdrawnNot Applicable
How Does Vagus Nerve Stimulation Affect Blood Glucose, Food, and Movement Cravings?
University of Minnesota1 site in 1 country8 target enrollmentStarted: September 1, 2026Last updated:
Interventions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Withdrawn
- Sponsor
- University of Minnesota
- Enrollment
- 8
- Locations
- 1
- Primary Endpoint
- Change in plasma glucose
Study Overview
Brief Summary
The purpose of this study is to determine the feasibility of using non-invasive transcutaneous auricular vagus nerve stimulation (taVNS) to examine physiological and psychological responses in a college-aged healthy population
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Basic Science
- Masking
- Single (Participant)
Eligibility Criteria
- Ages
- 18 Years to 35 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Participants must be between the ages of 18 and 35 as we are focused on recruiting undergraduate and graduate students.
Exclusion Criteria
- •Participants will be excluded if they have epilepsy, clinically significant tachycardia or arrhythmia, diabetes (Type 1 or Type 2) or another metabolic disease, current pregnancy, any implanted electronic medical device (for example, pacemaker or defibrillator), or a known skin allergy to adhesives that would prevent CGM placement. Participants will also be excluded if they have a history of major depressive disorder if taVNS could reasonably be expected to alter mood symptoms
Arms & Interventions
Active taVNS
Active Comparator
Intervention: Active taVNS (Device)
Sham taVNS
Placebo Comparator
Intervention: Sham taVNS (Device)
Outcomes
Primary Outcomes
Change in plasma glucose
Time Frame: Hour 2 after oral glucose load
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
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