Short-term clinical outcome of robotic-assisted esophagectomy for esophageal cancer: a retrospective single-center analysis.

• Conditions: C15; Malignant neoplasm of oesophagus

• Registration Number: DRKS00028112
• Lead Sponsor: niversitätsklinikum Münster (UKM)Klinik für Allgemein-, Viszeral- und Transplantationschirurgie

Brief Summary

This single-center, retrospective study employing propensity score matching found that combining robotic-assisted minimally invasive esophagectomy (RAMIE) with structured total mesoesophageal excision (TME) results in better short-term clinical and oncologic outcomes than open transthoracic esophagectomy without structured TME. This finding is significant because the increased rate of R0 resection could indicate a higher likelihood of improved long-term survival. Additionally, enhanced overall postoperative recovery may contribute to better risk management in esophagectomy procedures.

Detailed Description

Not available

Study Timeline

• Study Completion: 2022-04-30
• Study Start: 2022-06-15
• Results First Posted: 2024-06-29
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 270

Inclusion Criteria

Patients after esophagectomy who underwent either open, hybrid-laparoscopic, or robotic-assisted surgery.

period retrospective:
01.01.2012-15.03.2022

Exclusion Criteria

1. pregnancy / lactation
2. premature termination of surgery in case of inoperability
3. active COVID-19 infection / HSV pneumonia
4. multiple-stage esophagectomy (different days)

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
30d mortality-rate, R0-resection rate, severe complication rate (Clavien-Dindo)

Secondary Outcome Measures

Name	Time	Method
- ICU and hospital stay<br>- laboratory values<br>- postoperative complication rate: anastomotic leak & pneumonia<br>- possible confounder