IRCT20200408046990N7招募中2 期
Evaluation of oral nano-formulation of Curcumin efficacy, as an adjuvant to Capecitabine [Xeloda] + Oxaliplatin (XELOX) or Folinic Acid + 5-Flurouracil + Oxaliplatin (FOLFOX) regimen treatment for metastatic colorectal cancer: A triple blinded, randomized clinical trial
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 70 years（—）
- 性别
- All
入选标准
- •Patients with confirmed histological or cytological diagnosis of metastatic colorectal cancer (stage 4) Based on ultrasound results without NRAS and KRAS mutation or no candidate for target therapy(Contraindications or economic incapability)
- •XELOX or FOLFOX regimen candidate
- •Patient consent to study
- •Eastern cooperative oncology group (ECOG) 0/ 1
- •Hemoglobin=9g/dL? Neutrophil count=1.5×103/µL, Platelet count=10×104/µLCreatinine=1.5 mg/dl, ALT,AST =5 ×ULN? total bilirubin=2×
排除标准
- •current antioxidant users
- •pregnancy or lactation
- •history of hypersensitivity to formulation components
- •diagnosed with more than one cancer
- •history of HF
- •history of autoimmune or immunodeficiency (medical or drug induced) other than chemotherapy
- •history of HBV or HCV
- •candidate of curative surgery
研究者
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