Intraoperative Floppy Iris Syndrome in Korean Patients Taking α1-Adrenergic Receptor Antagonists

Completed

• Conditions: Intraoperative Floppy Iris Syndrome

• Registration Number: NCT01704014
• Lead Sponsor: Samsung Medical Center

Brief Summary

Intraoperative floppy iris syndrome (IFIS) is a recently described condition observed during cataract surgery. It has been hypothesized that irreversible atrophy of the iris dilator muscle associated with α1-adrenergic receptor antagonists (α1-ARA) is responsible for IFIS. However the prevalence of IFIS in Korean population is not reported. The purpose of this study is to evaluate the prevalence and clinical manifestations of IFIS in relation to iris anatomical change in Korean patients taking α1-ARA.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-01
• Primary Completion: 2010-03
• Study Completion: 2010-03
• Status Verified: 2012-10
• Study First Submitted: 2012-10-08
• Study First Submitted QC: 2012-10-10
• Last Update Submitted: 2012-10-10
• Study First Posted: 2012-10-11
• Last Update Posted: 2012-10-11

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• clinical diagnosis of cataract
• korean patients

Exclusion Criteria

• history of iridocyclitis, iris neovascularization, or prior iris surgery
• traumatic cataracts, zonular dialysis, or cataracts associated with ocular disease (e.g., uveitis)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
occurrence of intraoperative floppy iris syndrome	intraoperative