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Clinical Trials/CTRI/2025/11/097066
CTRI/2025/11/097066
Not Applicable
Not Applicable

An Observational Study on Emergence from Anaesthesia in Adults Following Sugammadex Administration as a Neuromuscular Blockade Reversal Agent

K S HEGDE MEDICAL ACADEMY1 site in 1 country52 target enrollmentStarted: November 20, 2025Last updated:

Overview

Phase
Not Applicable
Status
Not Applicable
Enrollment
52
Locations
1
Primary Endpoint
To compare recovery status in the postoperative period following reversal from general anaesthesia using Sugammadex and Neostigmine, using

Overview

Brief Summary

This study focuses on evaluating the effectiveness and timeline of patient awakening after general anaesthesia when sugammadex is used as a neuromuscular blockade reversal agent. Sugammadex, a modified gamma cyclodextrin, is specifically designed to reverse the effects of steroidal neuromuscular blocking agents, such as rocuronium and vecuronium. The research assesses parameters such as time to return of spontaneous respiration, eye opening, ability to follow verbal commands, and extubation readiness. It also compares the recovery profile of sugammadex with traditional reversal agents like neostigmine, aiming to determine its safety, efficacy, and potential benefits in improving post-anaesthesia recovery.

Study Design

Study Type
Observational

Eligibility Criteria

Ages
18.00 Year(s) to 60.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Patients aged 18-60 years ASA-PS I and II Expected surgical duration less than 3 hours Patients undergoing elective surgeries.

Exclusion Criteria

  • 1.Patient who cannot comprehend, uncooperative patient 2.Neuropsychiatric disease 3.Chronic alcohol or drug addict 4.Planned postoperative ICU Admission.

Outcomes

Primary Outcomes

To compare recovery status in the postoperative period following reversal from general anaesthesia using Sugammadex and Neostigmine, using

Time Frame: To compare recovery status in the postoperative period following reversal from general anaesthesia using Sugammadex and Neostigmine, using | 1.AVPU scale | 2.six screener test | 3.MiniCog test

1.AVPU scale

Time Frame: To compare recovery status in the postoperative period following reversal from general anaesthesia using Sugammadex and Neostigmine, using | 1.AVPU scale | 2.six screener test | 3.MiniCog test

2.six screener test

Time Frame: To compare recovery status in the postoperative period following reversal from general anaesthesia using Sugammadex and Neostigmine, using | 1.AVPU scale | 2.six screener test | 3.MiniCog test

3.MiniCog test

Time Frame: To compare recovery status in the postoperative period following reversal from general anaesthesia using Sugammadex and Neostigmine, using | 1.AVPU scale | 2.six screener test | 3.MiniCog test

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Private medical college
Responsible Party
Principal Investigator
Principal Investigator

DR M Venkat karli

K S Hegde Medical Academy

Study Sites (1)

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